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Protein Biochemistry
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Salubrinal
Salubrinal from Cayman Chemical
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Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
Salubrinal
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Description
A selective phosphatase inhibitor which prevents dephosphorylation of eIF2α, protecting cells from ER stress-mediated apoptosis (EC50 = 15 µM); prevents replication of herpes virus (IC50 = 3 µM) and alters bone formation
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Salubrinal
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
14735
Quantity
1 mg
Research Area
Apoptosis, Bone Growth & Remodeling, Cell Biology, Cell Death, Endocrinology & Metabolism, HSV, Infectious Disease, Viral Diseases
Format
A crystalline solid
Molecular Weight
479.8
Purity
≥95%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons
EBioMedicine
January 1, 2021
Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, Mori D, Ozaki N.
treated with tunicamycin (TCM;
T7765
,
Sigma-Aldrich
) for 24 h (from Day 23 to Day 24).
Salubrinal
(Sal;
14735
,
Cayman
),
GSK2656157
(
17372
,
Cayman
),
CCT020312
(324879,
Sigma-Aldrich
) and
Cycloheximide
(01810, Sigma-Aldrich)
(2)
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress
Cell stem cell
August 6, 2020
Guallar D, Fuentes-Iglesias A, Souto Y, Ameneiro C, Freire-Agulleiro O, Pardavila JA, Escudero A, Garcia-Outeiral V, Moreira T, Saenz C,
et al
.
T7765
) or 0.1 μM
Thapsigargin
(
Tocris
, 1138)] or ER stress alleviators [i.e. 1 μM of
Salubrinal
(
Cayman
,
14735
), 1 μM
Azoramide
(
Cayman
,
18045
)] at the indicated times during
reprogramming
. ER stress was also genetically
(3)
Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways
PLOS Biology
March 13, 2019
Mingwei Min, Sabrina L. Spencer
(
10008822
,
Cayman Chemical
, Ann Arbor, MI) at 1 μM; nutlin-3 (
10004372
,
Cayman Chemical
); salubrinal (
14735
,
Cayman Chemical
);
ganetespib (STA-9090
,
Selleckchem
); gemcitabine (
G6423
,
Sigma
); and hydrogen peroxide
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Salubrinal from Cayman Chemical
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